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Hemoglobin S - Making an Evolutionary Perfected Process, Imperfect 

Journal of Sickle Cell Disease and Hemoglobinoopathies

Meeting Location:

Greater Ft. Lauderdale Convention Center
1950 Eisenhower Blvd, Fort Lauderdale, Florida, USA  33316
April 28 - 30, 2017 
Website:  fscdr.org
Email:  symposium@fscdr.org
Is this a CME Medical Meeting?  Yes
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avatar for Jennell White, Ph.D.

Jennell White, Ph.D.

Wayne State University’s School of Medicine
Post-Doctoral Research Fellow

Dr. Jennell White is a post-doctoral research fellow in the lab of Dr. Patrick Hines at Wayne State University’s School of Medicine (WSU-SOM) in the Department of Pediatrics. Dr. White’s research focuses on mechanisms regulating sickle erythrocyte adhesive interactions during physiologic flow conditions.  Dr. White co-developed a process to utilize microliter whole blood volumes to establish normal ranges of adhesion indices in patients with SCD, to establish the relationship of standardized adhesion indices to vaso-occlusive pathology, and to assess the effect of disease modifying therapies.  This process has been utilized by numerous pharmaceutical companies and research scientists to objectively assess the effect of a wide range of therapies using adhesion as a biomarker. The emergence of novel, anti-adhesive therapies for sickle cell disease necessitate the adoption of standardized erythrocyte adhesion bioassays to define the relationship of adhesion to vaso-occlusive pathology and asses the effect of anti-adhesive drug therapy.  Dr. White is optimistic that her research will help to address this unmet need.